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	<title>Comments on: The HCG Diet: Another ineffective and possibly dangerous diet plan</title>
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	<link>http://sciencebasedpharmacy.wordpress.com/2012/07/19/the-hcg-diet-another-ineffective-and-possibly-dangerous-diet-plan/</link>
	<description>Turning an eye on the profession, separating fact from fiction on both sides of the counter</description>
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		<title>By: Caroline</title>
		<link>http://sciencebasedpharmacy.wordpress.com/2012/07/19/the-hcg-diet-another-ineffective-and-possibly-dangerous-diet-plan/#comment-7402</link>
		<dc:creator><![CDATA[Caroline]]></dc:creator>
		<pubDate>Thu, 20 Sep 2012 21:20:01 +0000</pubDate>
		<guid isPermaLink="false">http://sciencebasedpharmacy.wordpress.com/?p=4199#comment-7402</guid>
		<description><![CDATA[HCG drops worked perfectly for me!]]></description>
		<content:encoded><![CDATA[<p>HCG drops worked perfectly for me!</p>
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		<title>By: NB Holtslander</title>
		<link>http://sciencebasedpharmacy.wordpress.com/2012/07/19/the-hcg-diet-another-ineffective-and-possibly-dangerous-diet-plan/#comment-7265</link>
		<dc:creator><![CDATA[NB Holtslander]]></dc:creator>
		<pubDate>Thu, 06 Sep 2012 02:17:46 +0000</pubDate>
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		<description><![CDATA[In my experience, hcg drops did and do work.  I have tried many diets, none were satisfactory.  This one is ....and I am not hungry.  Why is it not studied...except with the converted against?]]></description>
		<content:encoded><![CDATA[<p>In my experience, hcg drops did and do work.  I have tried many diets, none were satisfactory.  This one is &#8230;.and I am not hungry.  Why is it not studied&#8230;except with the converted against?</p>
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		<title>By: Scott</title>
		<link>http://sciencebasedpharmacy.wordpress.com/2012/07/19/the-hcg-diet-another-ineffective-and-possibly-dangerous-diet-plan/#comment-7071</link>
		<dc:creator><![CDATA[Scott]]></dc:creator>
		<pubDate>Tue, 21 Aug 2012 23:08:46 +0000</pubDate>
		<guid isPermaLink="false">http://sciencebasedpharmacy.wordpress.com/?p=4199#comment-7071</guid>
		<description><![CDATA[@appel:

Actually, no. HCG has been studied, if you read the citations I link to.  It is demonstrably ineffective at modifying any relevant measure of obesity or weight loss.]]></description>
		<content:encoded><![CDATA[<p>@appel:</p>
<p>Actually, no. HCG has been studied, if you read the citations I link to.  It is demonstrably ineffective at modifying any relevant measure of obesity or weight loss.</p>
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		<title>By: appel</title>
		<link>http://sciencebasedpharmacy.wordpress.com/2012/07/19/the-hcg-diet-another-ineffective-and-possibly-dangerous-diet-plan/#comment-7061</link>
		<dc:creator><![CDATA[appel]]></dc:creator>
		<pubDate>Tue, 21 Aug 2012 08:01:47 +0000</pubDate>
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		<description><![CDATA[Belief, even your obviously strong belief, is not science. Take a closer look and ask yourself if there has yet been a study that evaluates HCG’s effectiveness in maintaining a diet protocol. There is more research to be done to establish conclusively that HCG does or does not work in weight loss.]]></description>
		<content:encoded><![CDATA[<p>Belief, even your obviously strong belief, is not science. Take a closer look and ask yourself if there has yet been a study that evaluates HCG’s effectiveness in maintaining a diet protocol. There is more research to be done to establish conclusively that HCG does or does not work in weight loss.</p>
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		<title>By: Scott</title>
		<link>http://sciencebasedpharmacy.wordpress.com/2012/07/19/the-hcg-diet-another-ineffective-and-possibly-dangerous-diet-plan/#comment-6990</link>
		<dc:creator><![CDATA[Scott]]></dc:creator>
		<pubDate>Sat, 11 Aug 2012 16:40:11 +0000</pubDate>
		<guid isPermaLink="false">http://sciencebasedpharmacy.wordpress.com/?p=4199#comment-6990</guid>
		<description><![CDATA[If you review the meta-analysis linked above, the number of patients lost to follow-up is noted for each included study. Most trials included had no dropouts in either arm, and there is no clear trend that patients in control arms were more likely to drop out, which would be expected if the drug had this effect.

If you are aware of data to show otherwise, please provide the citation.]]></description>
		<content:encoded><![CDATA[<p>If you review the meta-analysis linked above, the number of patients lost to follow-up is noted for each included study. Most trials included had no dropouts in either arm, and there is no clear trend that patients in control arms were more likely to drop out, which would be expected if the drug had this effect.</p>
<p>If you are aware of data to show otherwise, please provide the citation.</p>
]]></content:encoded>
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		<title>By: Barb</title>
		<link>http://sciencebasedpharmacy.wordpress.com/2012/07/19/the-hcg-diet-another-ineffective-and-possibly-dangerous-diet-plan/#comment-6989</link>
		<dc:creator><![CDATA[Barb]]></dc:creator>
		<pubDate>Sat, 11 Aug 2012 16:25:32 +0000</pubDate>
		<guid isPermaLink="false">http://sciencebasedpharmacy.wordpress.com/?p=4199#comment-6989</guid>
		<description><![CDATA[I did read the studies. Few include this detail in their written summaries of methodology, but in those that do, the count of subjects that start and complete the program differ according to their placement in HCG and placebo groups.

The data to answer this question aren&#039;t included because these studies evaluate efficacy for weight loss. And those from both groups that make it to the end generally lose about the same weight on the 500 calorie diet.

But, and this is huge, the studies removed from their calculations those who dropped out of the study. More importantly, a much higher number of placebo than HCG subjects dropped out. Ask yourself what keeping these subjects in the study would do to the calculation. Undoubtedly, weight loss among the HCG group would be statistically significantly higher.

In fairness to the researchers, these studies are designed to examine impact on weight loss, not the extent to which a person can stick to the diet. So I don&#039;t dispute the studies. But the study objectives, hence, conclusions don&#039;t match the intended use of HCG in weight loss.

I don&#039;t think a study has yet been completed that sets out to test this, but several of the studies already published do establish, if inadvertently, that HCG improves a subject&#039;s ability to stick to the low calorie program.

Belief, even your obviously strong belief, is not science. Take a closer look and ask yourself if there has yet been a study that evaluates HCG&#039;s effectiveness in maintaining a diet protocol. There is more research to be done to establish conclusively that HCG does or does not work in weight loss.]]></description>
		<content:encoded><![CDATA[<p>I did read the studies. Few include this detail in their written summaries of methodology, but in those that do, the count of subjects that start and complete the program differ according to their placement in HCG and placebo groups.</p>
<p>The data to answer this question aren&#8217;t included because these studies evaluate efficacy for weight loss. And those from both groups that make it to the end generally lose about the same weight on the 500 calorie diet.</p>
<p>But, and this is huge, the studies removed from their calculations those who dropped out of the study. More importantly, a much higher number of placebo than HCG subjects dropped out. Ask yourself what keeping these subjects in the study would do to the calculation. Undoubtedly, weight loss among the HCG group would be statistically significantly higher.</p>
<p>In fairness to the researchers, these studies are designed to examine impact on weight loss, not the extent to which a person can stick to the diet. So I don&#8217;t dispute the studies. But the study objectives, hence, conclusions don&#8217;t match the intended use of HCG in weight loss.</p>
<p>I don&#8217;t think a study has yet been completed that sets out to test this, but several of the studies already published do establish, if inadvertently, that HCG improves a subject&#8217;s ability to stick to the low calorie program.</p>
<p>Belief, even your obviously strong belief, is not science. Take a closer look and ask yourself if there has yet been a study that evaluates HCG&#8217;s effectiveness in maintaining a diet protocol. There is more research to be done to establish conclusively that HCG does or does not work in weight loss.</p>
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		<title>By: Scott</title>
		<link>http://sciencebasedpharmacy.wordpress.com/2012/07/19/the-hcg-diet-another-ineffective-and-possibly-dangerous-diet-plan/#comment-6987</link>
		<dc:creator><![CDATA[Scott]]></dc:creator>
		<pubDate>Sat, 11 Aug 2012 15:27:25 +0000</pubDate>
		<guid isPermaLink="false">http://sciencebasedpharmacy.wordpress.com/?p=4199#comment-6987</guid>
		<description><![CDATA[Except it doesn&#039;t. Read the studies and look at the endpoints measured. HCG has no effect.]]></description>
		<content:encoded><![CDATA[<p>Except it doesn&#8217;t. Read the studies and look at the endpoints measured. HCG has no effect.</p>
]]></content:encoded>
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		<title>By: Barb</title>
		<link>http://sciencebasedpharmacy.wordpress.com/2012/07/19/the-hcg-diet-another-ineffective-and-possibly-dangerous-diet-plan/#comment-6986</link>
		<dc:creator><![CDATA[Barb]]></dc:creator>
		<pubDate>Sat, 11 Aug 2012 15:14:32 +0000</pubDate>
		<guid isPermaLink="false">http://sciencebasedpharmacy.wordpress.com/?p=4199#comment-6986</guid>
		<description><![CDATA[The HCG doesn&#039;t aid in weight loss, and from what I understand, it doesn&#039;t claim to. The HCG helps the body use its fat stores. If you take a closer look at those studies, you&#039;ll find that the number of people who stuck to the diet in the double blind studies was remarkably higher among HCG users than Placebo users. The conclusion: Everyone will lose weight on a 500 calorie diet. But not everyone can stick to that diet without HCG.]]></description>
		<content:encoded><![CDATA[<p>The HCG doesn&#8217;t aid in weight loss, and from what I understand, it doesn&#8217;t claim to. The HCG helps the body use its fat stores. If you take a closer look at those studies, you&#8217;ll find that the number of people who stuck to the diet in the double blind studies was remarkably higher among HCG users than Placebo users. The conclusion: Everyone will lose weight on a 500 calorie diet. But not everyone can stick to that diet without HCG.</p>
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		<title>By: Epinephrine</title>
		<link>http://sciencebasedpharmacy.wordpress.com/2012/07/19/the-hcg-diet-another-ineffective-and-possibly-dangerous-diet-plan/#comment-6782</link>
		<dc:creator><![CDATA[Epinephrine]]></dc:creator>
		<pubDate>Mon, 23 Jul 2012 13:49:25 +0000</pubDate>
		<guid isPermaLink="false">http://sciencebasedpharmacy.wordpress.com/?p=4199#comment-6782</guid>
		<description><![CDATA[&lt;blockquote&gt;if Health Canada gives it the thumbs up, then there must be some validation to the diet.&lt;/blockquote&gt;

Unfortunately, no.  While pharmaceutical (and biologic) drug review is pretty thorough, the review of natural health products (as Scott has commented on in the past) is distressingly bad, with standards of evidence that accept traditional use, or &quot;expert opinion reports&quot; rather than solid clinical evidence.  Health Canada approval of a NHP is by itself rather meaningless, thanks to the watered-down evidence requirements.  While some NHPs may indeed live up to their claims, there is no guarantee that a claim can be trusted.]]></description>
		<content:encoded><![CDATA[<blockquote><p>if Health Canada gives it the thumbs up, then there must be some validation to the diet.</p></blockquote>
<p>Unfortunately, no.  While pharmaceutical (and biologic) drug review is pretty thorough, the review of natural health products (as Scott has commented on in the past) is distressingly bad, with standards of evidence that accept traditional use, or &#8220;expert opinion reports&#8221; rather than solid clinical evidence.  Health Canada approval of a NHP is by itself rather meaningless, thanks to the watered-down evidence requirements.  While some NHPs may indeed live up to their claims, there is no guarantee that a claim can be trusted.</p>
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		<title>By: Stacy</title>
		<link>http://sciencebasedpharmacy.wordpress.com/2012/07/19/the-hcg-diet-another-ineffective-and-possibly-dangerous-diet-plan/#comment-6734</link>
		<dc:creator><![CDATA[Stacy]]></dc:creator>
		<pubDate>Fri, 20 Jul 2012 03:01:15 +0000</pubDate>
		<guid isPermaLink="false">http://sciencebasedpharmacy.wordpress.com/?p=4199#comment-6734</guid>
		<description><![CDATA[Haha...injection]]></description>
		<content:encoded><![CDATA[<p>Haha&#8230;injection</p>
]]></content:encoded>
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